Table 2.
Inpatient characteristics by AKI stage from 24 hours prior to until 48 hours after admission.
| Stage 1 (n=443) | Stage 2 (n=199) | Stage 3 (n=80) | P Value | |
|---|---|---|---|---|
|
| ||||
| Age (y) | 6.4 (2.0 – 13.7) | 4.1 (2.0 – 8.8) | 4.2 (1.8 – 10.4) | < 0.0011 |
|
| ||||
| Male sex | 243 (55%) | 119 (60%) | 51 (64%) | 0.092 |
|
| ||||
| Hospital Length of Stay (d) | 4 (2 – 7) | 5 (3 – 10) | 5 (2 – 10) | 0.0011 |
|
| ||||
| Weight z-score | −0.2 (−1.2 – 0.8) | −0.8 (−1.9 – 0.2) | −0.3 (−1.3 – 0.7) | 0.0041 |
|
| ||||
| Total no. of Unique Medications | 4 (2 – 7) | 5 (2 – 7) | 4 (2 – 9) | 0.11 |
|
| ||||
| No. of group 1* medications given | 0.83 | |||
|
| ||||
| 0 | 257 (58%) | 119 (60%) | 51 (64%) | |
| 1 | 134 (30%) | 60 (30%) | 20 (25%) | |
| ≥2 | 52 (12%) | 20 (10%) | 9 (11%) | |
|
| ||||
| No. of group 2* medications given | <0.0011 | |||
|
| ||||
| 0 | 0: 349 (79%) | 0: 138 (69%) | 0: 53 (66%) | |
| 1 | 1: 79 (18%) | 1: 40 (20%) | 1: 16 (20%) | |
| ≥2 | =2: 15 (3%) | =2: 21 (11%) | =2: 11 (14%) | |
|
| ||||
| Contrast Given in Prior 7 Days | 30 (7%) | 9 (5%) | 3 (4%) | 0.21 |
Note: Values for categorical variables are given as number (percentage); for continuous variables, as median [interquartile range].
P values compare stages 1, 2, and 3 by the 1Proportional odds test, 2Cochran-Armitage trend test, or 3Pearson chi-squared test.
*
Groups 1 and 2 are nephrotoxic medications; see Methods.