Fig 2. Effect of the inhibitors on the accumulation and efflux of ethidium bromide by the M. tuberculosisstrains.

In the figure is presented an assay for strain M. tuberculosis 29/12 as an example. A) Accumulation and B) efflux of ethidium bromide. Ethidium bromide was tested at 0.25 μg/ml. Efflux inhibitors were tested at half MIC. EtBr, ethidium bromide. Accumulation assays: results were considered significant when *P < 0.05 (EtBr plus flupenthixol or thioridazine) and highly significant **P < 0.01 (verapamil and chlorpromazine). Efflux assays: **P < 0.01.