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. 2016 Feb 26;11(2):e0149326. doi: 10.1371/journal.pone.0149326

Fig 4. Antimycobacterial activity of the ion channel blockers against M. tuberculosis-infected macrophages.

Fig 4

Effect of the inhibitors on the intracellular survival of M. tuberculosis (Mtb) within human monocyte-derived macrophages, three days post infection. Isoniazid (INH) was tested at 0.1 μg/ml, verapamil (VP), 10 μg/ml; thioridazine (TZ), 2.5 μg/ml; chlorpromazine (CPZ), 1.25 μg/ml; haloperidol (HAL), 1.25 μg/ml; flupenthixol (FPX), 1.25 μg/ml. The results are presented as a mean of the percentage of the survival ± SD. RIF, rifampicin; R, resistant; MDR, multidrug resistant; XDR, extensively drug resistant. The results were considered significant when *P < 0.05 and highly significant when **P < 0.01.