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. 2016 Feb 16;5:e09976. doi: 10.7554/eLife.09976
Figure 2B; assumed number of biological replicates = 3
hairpin Dox Drug Dose Normalized pMEK
band density
shBRAF - GDC-0879 0 0.1453
shBRAF - GDC-0879 0.1 0.8004
shBRAF - GDC-0879 1.0 0.1263
shBRAF - GDC-0879 10.0 0.0245
shBRAF + GDC-0879 0 0.0457
shBRAF + GDC-0879 0.1 0.6477
shBRAF + GDC-0879 1.0 0.1485
shBRAF + GDC-0879 10.0 0.0115
shBRAF - PLX4720 0 0.0795
shBRAF - PLX472 0.1 0.1615
shBRAF - PLX472 1.0 0.7760
shBRAF - PLX472 10.0 1.0721
shBRAF + PLX472 0 0.0861
shBRAF + PLX472 0.1 0.1388
shBRAF + PLX472 1.0 0.4522
shBRAF + PLX472 10.0 0.9831
shCRAF - GDC-0879 0 0.2121
shCRAF - GDC-0879 0.1 0.7038
shCRAF - GDC-0879 1.0 0.1554
shCRAF - GDC-0879 10.0 0.0239
shCRAF + GDC-0879 0 0.1005
shCRAF + GDC-0879 0.1 0.1896
shCRAF + GDC-0879 1.0 0.0933
shCRAF + GDC-0879 10.0 0.0315
shCRAF - PLX4720 0 0.4166
shCRAF - PLX472 0.1 0.7469
shCRAF - PLX472 1.0 1.1387
shCRAF - PLX472 10.0 1.2976
shCRAF + PLX472 0 0.2945
shCRAF + PLX472 0.1 0.2449
shCRAF + PLX472 1.0 0.2983
shCRAF + PLX472 10.0 0.2729