Table 3.
Multivariable association of the severity of AKI on subsequent development of elevated BP after hospital discharge
| Period after Hospital Discharge (d) | ||||
|---|---|---|---|---|
| 180 (n=40,861) | 365 (n=42,845) | 540 (n=43,407) | 730 (n=43,611) | |
| No. of subjects with AKI | ||||
| Stage 1 AKI | 1667 | 1721 | 1731 | 1741 |
| Stage 2 AKI | 367 | 372 | 373 | 374 |
| Stage 3 AKI | 333 | 333 | 334 | 336 |
| Unadjusted OR for elevated BP postdischargea | ||||
| Stage 1 AKI versus no AKI | 1.23 | 1.2 | 1.13 | 1.09 |
| 95% CI | 1.11 to 1.38 | 1.09 to 1.33 | 1.03 to 1.25 | 0.99 to 1.20 |
| Stage 2 AKI versus no AKI | 1.65 | 1.51 | 1.49 | 1.42 |
| 95% CI | 1.33 to 2.05 | 1.23 to 1.86 | 1.22 to 1.83 | 1.16 to 1.75 |
| Stage 3 AKI versus no AKI | 2.18 | 2.13 | 1.88 | 1.81 |
| 95% CI | 1.75 to 2.72 | 1.72 to 2.65 | 1.52 to 2.33 | 1.46 to 2.25 |
| Adjustedb OR for elevated BP postdischargea | ||||
| Stage 1 AKI versus no AKI | 1.23 | 1.21 | 1.13 | 1.09 |
| 95% CI | 1.10 to 1.37 | 1.09 to 1.34 | 1.02 to 1.26 | 0.98 to 1.21 |
| Stage 2 AKI versus no AKI | 1.66 | 1.53 | 1.51 | 1.45 |
| 95% CI | 1.32 to 2.08 | 1.23 to 1.90 | 1.22 to 1.87 | 1.17 to 1.79 |
| Stage 3 AKI versus no AKI | 2.18 | 2.17 | 1.89 | 1.82 |
| 95% CI | 1.74 to 2.74 | 1.73 to 2.71 | 1.52 to 2.37 | 1.45 to 2.29 |
a
Defined as systolic BP>140 mmHg and/or diastolic BP>90 mmHg during follow-up.
b
Adjusted for age at index hospitalization, sex, race, body mass index, last ambulatory systolic and diastolic BP measurements, smoking status, diabetes mellitus, chronic heart failure, coronary heart disease, last ambulatory eGFR, and proteinuria.