Table 4.
Development of major events between baseline and 2-year follow-up
| Group/Event | Patients at Baseline | Patients at 2-y Follow-Up | P Value | Additional Patients |
|---|---|---|---|---|
| Regular-dose | ||||
| TIA/strokes | 2 (8.7) | 2 (8.7) | 0.99 | 0 |
| Dialysis | 8 (34.8) | 8 (34.8) | 0.99 | 0 |
| Kidney transplantation | 3 (13.0) | 4 (17.4) | 0.99 | 1 |
| Pacemaker/ICD | 3 (13.0) | 4 (17.4) | 0.99 | 1 |
| Dose-reduction-switch | ||||
| TIA/strokes | 0 (0.0) | 3 (15.8) | 0.23 | 3 |
| Dialysis | 4 (14.8) | 5 (18.5) | 0.99 | 1 |
| Kidney transplantation | 4 (14.8) | 4 (14.8) | 0.99 | 0 |
| Pacemaker/ICD | 2 (7.7) | 3 (11.5) | 0.99 | 1 |
| Switch | ||||
| TIA/strokes | 1 (3.6) | 2 (7.1) | 0.99 | 2 |
| Dialysis | 5 (14.7) | 5 (14.7) | 0.99 | 1a |
| Kidney transplantation | 2 (5.9) | 3 (8.8) | 0.99 | 1 |
| Pacemaker/ICD | 2 (6.3) | 3 (9.4) | 0.99 | 1 |
Values are given as n (%) or as otherwise indicated. TIA, transitory ischemic attack; ICD, implantable cardioverter defibrillator.
a
One patient stopped dialysis and received kidney transplantation.