Testis size and gene expression in D3 and D2 double deficiency. A, Relative testis weight in adult mice of the 4 genotypes. B and C, Testicular expression of Hr and Amh mRNAs, respectively, in P5 animals. D, Testicular gene expression of Inhba, Fst, and Hr mRNAs in adult mice. Data represent the mean ± SEM of determinations in 4–9 animals per group. Statistical significance was determined by the ANOVA and Tukey's post hoc test; *, P < .05; **, P < .01; ***, P < .001, respectively, when compared with the WT group; #, P < .05, when compared with the D3KO group.