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Characterization of the metabolic phenotypes of male VGFflpflox/flpflox mice receiving rAAV-Cre. A, Body weight. B, Weight gain. C, Glucose tolerance test 5 weeks after rAAV injection. Oxygen consumption (VO2) (D), RER (E), physical activity (F), and food consumption (G) measured by CLAMS. Shaded area, dark phase. H, Rectal temperature measured 6 weeks after rAAV-Cre injection. Data are mean ± SEM, n = 10 YFP, n = 11 Cre; *, P < .05; #, P = .06.
