Table 4a. Multivariable Analysis for Predictors of Venous Thromboembolism in Cancer Patients.
Characteristic | OR | 95% CI* | P-Value* | |
---|---|---|---|---|
Two-fold increase in Cancer site VTE risk score | 1.37 | 1.09 | 1.71 | 0.007 |
Lymphoma: Low Grade | 0.26 | 0.09 | 0.70 | 0.008 |
Lymphoma: Intermediate or High Grade | 1.42 | 0.50 | 4.03 | 0.51 |
Myeloproliferative neoplasm | 38.99 | 8.72 | 174.26 | <.001 |
Stage 2 or 3 or 4 | 2.18 | 1.56 | 3.02 | <.001 |
Metastasis to liver | 2.70 | 1.69 | 4.31 | <.001 |
Chemotherapy use within 92 days | 1.81 | 1.17 | 2.81 | 0.008 |
Progestin use within 92 days | 2.13 | 1.07 | 4.25 | 0.032 |
Body mass index (BMI) (Reference: 18.5-25 kg/m2) | ||||
BMI <18.5 kg/m2 (Underweight) | 1.93 | 1.02 | 3.66 | 0.044 |
BMI 25-30 kg/m2 (Overweight) | 1.10 | 0.76 | 1.61 | 0.61 |
BMI 30-35 kg/m2 (Obese class I) | 1.67 | 0.98 | 2.86 | 0.062 |
BMI ≥35 kg/m2 (Obese class II-III) | 3.97 | 1.48 | 10.66 | 0.006 |
Location of onset of VTE (Reference: Community) | ||||
Nursing home | 4.71 | 2.01 | 11.04 | <.001 |
Hospitalized within 92 days | 3.89 | 2.53 | 5.97 | <.001 |
Hospitalized | 7.91 | 4.44 | 14.10 | <.001 |
CV catheter use within 92 days | 8.53 | 2.76 | 26.40 | <.001 |
Any infection within 92 days | 1.71 | 1.19 | 2.45 | 0.004 |
95% Confidence intervals are calculated using the robust sandwich estimate of Lin and Wei [54] for the covariance and standard error. P-values are Wald p-values from the conditional logistic model using the robust sandwich estimate.