Table 1.
Changes in the patient's metabolic parameters at each follow-up
| After changes in treatment regimen |
|||||
|---|---|---|---|---|---|
| Initial visit | 3 months | 6 months | 12 months | 18 months | |
| Body weight (kg) | 61.5 | 53.7 | 57.6 | 61.6 | 63.6 |
| BMI (kg/m2) | 21.8 | 19.0 | 20.4 | 21.8 | 22.5 |
| HbA1c (%) | 8.4 | 5.8 | 6.6 | 8.5 | 9.4 |
| Plasma glucose (mg/dL) | |||||
| Fasting | 122 | 106 | |||
| At random | 107 | 152 | 225 | ||
| Fasting insulin (μU/L) | 29.7 | 28.2 | |||
| Urinary CPR (μg/day) | 257 | 143 | |||
| Fasting leptin (ng/mL) | 2.7 | 6.3 | |||
| Triglyceride (mg/dL) | 331 | 237 | 396 | 327 | 238 |
| Total cholesterol (mg/dL) | 291 | 220 | 276 | 245 | 198 |
| HDL cholesterol (mg/dL) | 44 | 58 | 58 | 52 | 57 |
| LDL cholesterol (mg/dL) | 181 | 115 | 139 | 128 | 93 |
| AST (U/L) | 63 | 27 | 29 | 48 | 50 |
| ALT (U/L) | 45 | 20 | 19 | 38 | 44 |
| Serum creatinine (mg/dL) | 1.18 | 1.49 | 1.29 | 1.35 | 1.25 |
| TSH (μU/mL) | 15.5 | 0.80 | 1.86 | 5.96 | 4.04 |
| Free T4 (ng/dL) | 1.02 | 1.17 | 1.02 | 1.12 | 1.10 |
| Free T3 (pg/mL) | 2.9 | 2.8 | 3.0 | 3.0 | 2.6 |
| CD4 cell count (/μL) | 279 | 204 | 204 | 263 | 184 |
ALT, alanine transaminase; AST, aspartate transaminase; CPR, C peptide reactivity; HbA1c, glycated haemoglobin; HDL, high-density lipoprotein; LDL, low-density lipoprotein; T3, tri-iodothyronine; T4, thyroxine; TSH, thyroid-stimulating hormone.