Table 1.
Description of Maffucci patients with or without neoplasms worldwide
| Number of patients with Maffucci syndrome | Number of osteosarcoma cases | Number of non-skeletal neoplasms | Kind of non-skeletal neoplasms | Follow-up | Year of publication | References |
|---|---|---|---|---|---|---|
| 1 | 1 probably malignant transformation of a clavicular lesion | 0 | No | 1881 | [11] | |
| 0 | 3 | Astrocytoma, pituitary adenomas, juvenile granulosa cell tumor | 1973 | [12] | ||
| 7 | 4 (three of them had two neoplasms each) | 3 | BC, PC, astrocytoma | Yes | 1987 | [8] |
| 1 | 0 | 1 | Astrocytoma | 1987 | [13] | |
| 1 | 0 | 1 | Astrocytoma | 1990 | [14] | |
| 1 | 0 | 1 | Ovarian fibrosarcoma | No | 1990 | [15] |
| 1 | 0 | 1 | Astrocytoma | 1991 | [16] | |
| 1 | 0 | 0 | No | 2001 | [17] | |
| 17 | 9/17 (53 %) | 0 | Yes | 2011 | [10] | |
| 1 | 1 | 1 | Hemangioendothelioma | Yes | 2012 | [18] |
| 1 | 1 | 0 | No | 2012 | [19] | |
| 1 | 0 | 1 | Spindle cell hemangioma | No | 2013 | [20] |
| 1 | 1 | 0 | No | 2013 | [11] | |
| 1 | 0 | 0 | No | 2013 | [21] | |
| 1 | 0 | 1 | Anaplastic astrocytoma | No | 2014 | [22] |
| 1 | 1 | 0 | No | 2014 | [23] | |
| 1 | 0 | 0 | No | 2014 | [24] | |
| 1 | 1 | 0 | No | 2014 | [25] | |
| 1 | 1 | 0 | No | 2014 | [26] | |
| 9 | 1 | 1 | Acute myeloid leukemia and von Willebrand disease | No | 2014 | [27] |
| 1 | 1 | 0 | No | 2015 | [28] | |
| 1 | 1 | 0 | No | 2015 | [29] | |
| 1 | 1 | 0 | No | 2015 | [30] | |
| 1 | 0 | 0 | No | 2015 | [31] |
PC pancreatic cancer, BC biliary adenocarcinoma