Table 2.
Relationship between antibody levels and age
| Burkina Faso | Ghana | ||||||
|---|---|---|---|---|---|---|---|
| Antibody | Antigen | Coefficient (95 % CI) | p value | Adjusted R2 | Coefficient (95 % CI) | p value | Adjusted R2 |
| IgG | GLURP R2 | 6.69 (4.10, 10.91) | <0.0001 | 0.14 | 2.82 (0.97, 8.23) | 0.057 | 0.013 |
| MSP1-hybrid | 9.28 (4.75, 18.13) | <0.0001 | 0.11 | 1.56 (4.10, 5.93) | 0.51 | 0 | |
| AS202.11 | 2.23 (1.33, 4.28) | 0.0037 | 0.021 | 0.86 (0.35, 2.14) | 0.73 | 0 | |
| IgG1 | GLURP R2 | 5.55 (2.91, 10.60) | <0.0001 | 0.069 | 3.09 (1.00, 9.61) | 0.051 | 0.014 |
| MSP1-hybrid | 2.08 (0.63, 6.83) | 0.23 | 0.0013 | 0.71 (0.37, 1.36) | 0.3 | 0.0004 | |
| IgG2 | GLURP R2 | 10.37 (6.00, 17.94) | <0.0001 | 0.16 | 2.39 (0.70, 8.12) | 0.16 | 0.0047 |
| MSP1-hybrid | 21.88 (6.98, 68.57) | <0.0001 | 0.072 | 1.00 (0.28, 3.66) | 1 | 0 | |
| IgG3 | GLURP R2 | 6.16 (4.02, 9.43) | <0.0001 | 0.16 | 2.93 (1.20, 7.16) | 0.019 | 0.021 |
| MSP1-hybrid | 2.81 (1.85, 4.26) | <0.0001 | 0.061 | 3.09 (0.90, 1.06) | 0.073 | 0.011 | |
| IgG4 | GLURP R2 | 2.76 (1.62, 4.71) | 0.00021 | 0.036 | 8.81 (0.94, 82.24) | 0.056 | 0.013 |
| MSP1-hybrid | 1.88 (0.96, 3.68) | 0.064 | 0.0069 | 3.42 (0.62, 18.77) | 0.16 | 0.005 | |
| IgM | GLURP R2 | 36.64 (14.83, 90.52) | <0.0001 | 0.15 | 35 (5.01, 248.77) | 0.0004 | 0.054 |
| MSP1-hybrid | 8.76 (3.18, 24.12) | <0.0001 | 0.045 | 7.62 (1.05, 55.45) | 0.045 | 0.015 | |
| AS202.11 | 3.60 (1.75, 7.41) | 0.00055 | 0.031 | 6.86 (1.20, 3.93) | 0.031 | 0.018 | |
Coefficient, 95 % confidence level (CI), p values and adjusted R2 values were calculated from univariate linear regression models