Table 4.

Smokescreen addiction genes: source, categories, and counts*

Source	Category	Genes
Gene Ontology	dopamine_receptor_binding	8
Gene Ontology	dopamine_binding	9
Gene Ontology	serotonin_uptake	4
Gene Ontology	serotonin_metabolic_process	8
Gene Ontology	serotonin_transport	12
Gene Ontology	response_to_nicotine	31
Gene Ontology	dopamine_secretion	15
Gene Ontology	dopamine_uptake	8
Gene Ontology	dopamine_receptor_signaling_pathway	30
Gene Ontology	dopamine_transport	23
Gene Ontology	serotonin_secretion	8
Gene Ontology	dopamine_metabolic_process	26
Gene Ontology	regulation_of_dopamine_secretion	15
IPA	cigarette_habituation_susceptibility_syndrome	6
IPA	nicotine	14
IPA	susceptibility_to_drug_addiction	1
IPA	addiction_behavior	24
IPA	tobacco	27
IPA	addiction	131
IPA	withdrawal	11
IPA	smoking	12
IPA	naltrexone	4
IPA	clonidine	7
IPA	nortripyline	3
IPA	varenicline	3
IPA	nicotine	19
IPA	bupropion	3
NIDA Genetics Consortium	The Nicotine System	20
NIDA Genetics Consortium	The Dopamine System	10
NIDA Genetics Consortium	Mouse QTL	423
NIDA Genetics Consortium	The Alcohol System	32
NIDA Genetics Consortium	The Cholinergic System	9
NIDA Genetics Consortium	The Adrenergic System	16
NIDA Genetics Consortium	Tyrosine	3
NIDA Genetics Consortium	Other	263
NIDA Genetics Consortium	The GABA System	31
NIDA Genetics Consortium	Neurotransmitter Transporters	13
NIDA Genetics Consortium	The Nicotine Metabolism System	11
NIDA Genetics Consortium	The Serotonergic System	20
NIDA Genetics Consortium	The Endocannabinoid System	2
NIDA Genetics Consortium	Dopamine Synthesis	2
NIDA Genetics Consortium	The Glutamatergic System	42
NIDA Genetics Consortium	The Opioid System	12
PNAT		134

*Genes in categories may overlap