Table 2.
Patient characteristics of patients included pre- and post-intervention
| Pre-intervention | Post-intervention | P-value | |||
|---|---|---|---|---|---|
| n | (%) | n | (%) | ||
| Study participants | 253 | 155 | |||
| Female | 126 | (49.8) | 75 | (48.4) | NS |
| Age, years | NS | ||||
| Mean (range) | 71.4 | (78) | 72.1 | (75) | |
| Median | 73.0 | 73.0 | |||
| Infection | |||||
| AECOPD | 104 | (41.4) | 45 | (29.0) | 0.014 |
| Community-acquired pneumonia | 149 | (58.9) | 110 | (71.0) | |
| Nursing home residents | 25 | (9.9) | 9 | (5.8) | NS |
| Penicillin allergy | 32 | (12.6) | 9 | (5.8) | 0.03 |
| Risk factors for non-common bacteria or resistant bacteria | |||||
| Malignity or immunocompromised | 36 | (14.2) | 24 | (15.5) | NS |
| Preceding hospitalization last 30d | 57 | (22.5) | 24 | (15.5) | NS |
| Microbiological diagnostics | |||||
| Blood culture | 172 | (68.0) | 125 | (80.6) | 0.005 |
| Nasopharynx and/or expectorate | 205 | (81.0) | 141 | (91.0) | 0.007 |
| Pneumococcal urinary antigen test | 149 | (58.9) | 92 | (59.4) | NS |
| Othera | 157 | (62.1) | 104 | (67.1) | NS |
| None | 16 | (6.3) | 5 | (3.2) | NS |
| Aetiology | |||||
| S.pneumoniae | 30 | (11.9) | 16 | (10.3) | NS |
| H.influenzae | 12 | (4.7) | 13 | (8.4) | NS |
| Other bacteria | 15 | (5.9) | 11 | (7.1) | NS |
| Influenza virus A or B | 24 | (9.6) | 18 | (11.6) | NS |
| Other respiratory viruses | 34 | (13.4) | 30 | (19.4) | NS |
| None identified | 159 | (62.8) | 89 | (57.4) | NS |
| CRB-65 score | NS | ||||
| 0 | 25 | (16.8) | 16 | (14.5) | |
| 1 | 57 | (38.3) | 42 | (38.2) | |
| 2 | 48 | (32.2) | 32 | (29.1) | |
| 3 | 7 | (4.7) | 11 | (10.0) | |
| 4 | 2 | (1.3) | 1 | (0.9) | |
| Missing data | 10 | (6.7) | 8 | (7.3) | |
| Clinical outcomes | |||||
| Length of stay, median (range) | 5.3 | (34) | 5.9 | (33) | NS |
| 30 day mortality | 18 | (7.1) | 14 | (9.0) | NS |
| 30 day readmission | 55 | (22.8) | 24 | (16.7) | NS |