Table 2.
Pre-intervention | Post-intervention | P-value | |||
---|---|---|---|---|---|
n | (%) | n | (%) | ||
Study participants | 253 | 155 | |||
Female | 126 | (49.8) | 75 | (48.4) | NS |
Age, years | NS | ||||
Mean (range) | 71.4 | (78) | 72.1 | (75) | |
Median | 73.0 | 73.0 | |||
Infection | |||||
AECOPD | 104 | (41.4) | 45 | (29.0) | 0.014 |
Community-acquired pneumonia | 149 | (58.9) | 110 | (71.0) | |
Nursing home residents | 25 | (9.9) | 9 | (5.8) | NS |
Penicillin allergy | 32 | (12.6) | 9 | (5.8) | 0.03 |
Risk factors for non-common bacteria or resistant bacteria | |||||
Malignity or immunocompromised | 36 | (14.2) | 24 | (15.5) | NS |
Preceding hospitalization last 30d | 57 | (22.5) | 24 | (15.5) | NS |
Microbiological diagnostics | |||||
Blood culture | 172 | (68.0) | 125 | (80.6) | 0.005 |
Nasopharynx and/or expectorate | 205 | (81.0) | 141 | (91.0) | 0.007 |
Pneumococcal urinary antigen test | 149 | (58.9) | 92 | (59.4) | NS |
Othera | 157 | (62.1) | 104 | (67.1) | NS |
None | 16 | (6.3) | 5 | (3.2) | NS |
Aetiology | |||||
S.pneumoniae | 30 | (11.9) | 16 | (10.3) | NS |
H.influenzae | 12 | (4.7) | 13 | (8.4) | NS |
Other bacteria | 15 | (5.9) | 11 | (7.1) | NS |
Influenza virus A or B | 24 | (9.6) | 18 | (11.6) | NS |
Other respiratory viruses | 34 | (13.4) | 30 | (19.4) | NS |
None identified | 159 | (62.8) | 89 | (57.4) | NS |
CRB-65 score | NS | ||||
0 | 25 | (16.8) | 16 | (14.5) | |
1 | 57 | (38.3) | 42 | (38.2) | |
2 | 48 | (32.2) | 32 | (29.1) | |
3 | 7 | (4.7) | 11 | (10.0) | |
4 | 2 | (1.3) | 1 | (0.9) | |
Missing data | 10 | (6.7) | 8 | (7.3) | |
Clinical outcomes | |||||
Length of stay, median (range) | 5.3 | (34) | 5.9 | (33) | NS |
30 day mortality | 18 | (7.1) | 14 | (9.0) | NS |
30 day readmission | 55 | (22.8) | 24 | (16.7) | NS |