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. 2016 Feb 27;16:96. doi: 10.1186/s12879-016-1426-1

Table 4.

Monthly prescribing of appropriate empirical antibiotics and total treatment duration, estimated with interrupted times series

Appropriate empirical antibioticsa Total treatment duration
Percent P-value SE Days P-value SE
Intercept β0 68.3 5.3 11.5 0.4
Trend before intervention β1 −1.3 ns 0.9 −0.07 ns 0.1
Effect one month after intervention β2 14.1 ns 8.5 −1.4 0.04 0.9
Effect six month after intervention β2 45.4 0.002 11.0 0.57 ns 0.8
Trend change after intervention β3 4.1 0.02 2.9 0.27 0.03 0.14

Trends pre- and post intervention, and effect of the intervention on prescribing one and six months after the intervention (level change) are reported

aComprise benzylpenicillin in monotherapy, benzylpenicillin in combination with gentamicin, or amoxicillin/ampicillin, ns; data is considered non-significant when P > 0.05, SE Standard error