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. Author manuscript; available in PMC: 2016 May 1.
Published in final edited form as: Clin Exp Allergy. 2015 May;45(5):940–952. doi: 10.1111/cea.12481

Fig. 1.

Fig. 1

Time course of changes in RELM-β expression, procollagen and collagen production and ECM protein mRNA expression in the single challenge murine model. (a) Outline of sensitisation, challenge and sampling protocol in RELM-β−/− and wild-type (wt) C57BL/6 mice (n signifies naïve controls). (b) RELM-β protein concentrations in BAL fluid from wt mice (mean ± SEM of n = 3–6, *P < 0.05; one-way anova). (c) Collagen and procollagen concentrations in lung tissue of wt mice assessed by Sircol assay. Data are expressed as mean ± SEM of fold changes compared with naive control values. (d) Expression of extracellular matrix-related protein mRNA in wild-type and RELM-β-deficient mice (mean ± SEM of n = 3–6). *P < 0.05; one- or two-way anova (comparing wt animals with RELM-β −/− animals) with Bonferroni's correction.