Fig. 2.
(a) Photomicrographs showing immunoreactivity for RELM-β in bronchial biopsy sections from an asthmatic and a control subject. Some RELM-β+ cells are indicated by red arrows. (b) Numbers of RELM-β+ cells in sections of bronchial biopsies from controls (n = 23) and asthmatics (n = 18). (c) Correlation of RELM-β+ cells with lung function (FEV1) of the asthmatics. (d) Mean (±SEM) % of total submucosal RELM-β+ cells accounted by cells of the stated phenotypes. (e) Percentages of total submucosal cells of each phenotype expressing RELM-β (n = 18). CD68, CD68+ macrophages; CD31, CD31+ endothelial cells; 5B5, 5B5+ fibroblasts; Tryp, tryptase+ mast cells; Elas, elastase+ neutrophils; CD3; CD3+ T cells; MBP, MBP+ eosinophils. Mann–Whitney U-test was used for comparison between groups and Spearman's rank-order method with correction was used for the correlations.
