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. 2016 Feb 27;6:18. doi: 10.1186/s13550-016-0165-z

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© Xiao et al. 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 1 — Structures of three focused OBOC libraries and binding affinity of various peptide ligands for α3β1 integrin-expressing glioblastoma cells by flow cytometry. The focused OBOC libraries were designed and synthesized (a). Three glioblastoma cell lines U-87MG, U-118MG, and U-251MG were incubated with biotinylated LXY1 (blue curve), LXY4 (orange curve), LXY7 (green curve), LXY30 (red curve), or negative control (black curve) and then analyzed with flow cytometry (b)