Table 4.
Rating | Patients (n = 12) | Caregivers (n = 5) | Healthcare professionals (n = 10) | ||||||
---|---|---|---|---|---|---|---|---|---|
Mean abatacept autoinjector rating | Mean competitor autoinjector rating | Mean paired difference | Mean abatacept autoinjector rating | Mean competitor autoinjector rating | Mean paired difference | Mean abatacept autoinjector rating | Mean competitor autoinjector rating | Mean paired difference | |
(A) Formative study | |||||||||
Comfort | 6.6 | 4.6 | P = 0.0033 | 7.0 | 4.2 | P = 0.0135 | 6.8 | 4.5 | P < 0.0001 |
Control | 6.8 | 4.6 | P = 0.0025 | 7.0 | 4.0 | P = 0.0132 | 6.7 | 4.6 | P = 0.0095 |
Ease of use | 7.0 | 5.9 | P = 0.0006 | 7.0 | 5.2 | P = 0.0533 | 6.8 | 5.2 | P = 0.0046 |
Confidence of dose | 6.8 | 6.3 | P = 0.0819 | 7.0 | 5.8 | P = 0.2080 | 6.4 | 5.6 | P = 0.2999 |
Overall acceptability | 6.7 | 5.2 | P = 0.0001 | 7.0 | 4.6 | P = 0.0093 | 6.8 | 5.1 | P = 0.0020 |
Rating | Patients (n = 25) | Caregivers (n = 12) | Healthcare professionals (n = 13) | ||||||
---|---|---|---|---|---|---|---|---|---|
Mean abatacept autoinjector rating | Mean competitor autoinjector rating | Mean paired difference | Mean abatacept autoinjector rating | Mean competitor autoinjector rating | Mean paired difference | Mean abatacept autoinjector rating | Mean competitor autoinjector rating | Mean paired difference | |
(B) Summative study | |||||||||
Comfort | 6.4 | 5.2 | P = 0.0157 | 6.4 | 5.4 | P = 0.0671 | 6.8 | 5.2 | P = 0.0017 |
Control | 6.9 | 5.6 | P = 0.0002 | 6.9 | 5.8 | P = 0.0081 | 6.8 | 4.5 | P = 0.0001 |
Ease of use | 6.5 | 5.8 | P = 0.0210 | 6.8 | 5.8 | P = 0.0039 | 6.6 | 5.0 | P = 0.0012 |
Confidence of dose | 6.4 | 6.4 | P = 0.8960 | 6.8 | 6.3 | P = 0.2098 | 6.7 | 5.2 | P = 0.0112 |
Overall acceptability | 6.5 | 5.9 | P = 0.0404 | 6.8 | 5.8 | P = 0.0047 | 6.8 | 5.1 | P = 0.0002 |
Each score was quantified using a 7-point scale, where 1 = very unacceptable, 4 = neutral, and 7 = very acceptable
Analyses were restricted to those participants who provided both abatacept and competitor autoinjector ratings