Table 3.
Frequencies of micronuclei and nuclear abnormalities in farmers from the Maneadero valley and children.
| Women (n = 71) | Children (n = 72) | |||||
|---|---|---|---|---|---|---|
| Farmers (n = 37) | Unexposed (n = 34) | p value | Farmers (n = 34) |
Unexposed (n = 38) | p value | |
| Age | 35.5 ± 12.4 | 27.7 ± 9.4 | 0.0047 | 7.8 ± 3.2 | 10.3 ± 3.4 | 0.0111 |
| MNc | 4.5 ± 5.5 | 0.7 ± 0.9 | <0.0001 | 2.5 ± 2.5 | 0.1 ± 0.2 | <0.0001 |
| LN | 2.5 ± 3.7 | 2.6 ± 2.5 | 0.3512 | 3.7 ± 5.3 | 0.7 ± 2.3 | <0.0001 |
| BN | 3.1 ± 2.9 | 2.6 ± 2.1 | 0.7317 | 2.2 ± 2.0 | 2.3 ± 2.0 | 0.2833 |
| KR | 2.1 ± 4.4 | 1.0 ± 2.3 | 0.2480 | 3.0 ± 5.1 | 1.0 ± 1.2 | 0.9863 |
| CC | 2.0 ± 3.4 | 0.8 ± 1.7 | 0.0376 | 2.4 ± 4.2 | 0.1 ± 0.3 | <0.0001 |
| PN | 0.3 ± 0.6 | 2.0 ± 2.3 | <0.0001 | 0.3 ± 0.5 | 1.4 ± 1.8 | 0.0043 |
| KL | 6.4 ± 12.1 | 1.2 ± 1.6 | 0.0558 | 4.4 ± 6.4 | 4.3 ± 3.1 | 0.0617 |
MNc = micronucleated cells; LN = lobulated nucleus; BN = binucleated cells; PN = pyknotic cells; CC = condensed chromatin; KR = karyorrhexis; KL = karyolysis. Results are presented as mean ± SD from number of occurrences per 2000 counted cells. p value was obtained with the Mann-Whitney U test.