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. 2016 Feb 27;17:149. doi: 10.1186/s12864-016-2494-8

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© Baheti et al. 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Methylation ratio auto-correlation of CpGs at fixed distances before and after end repair C removal. Autocorrelation plot shows the correlation among neighbouring CpG sites (y-axis) dependents on the distance between two sites compared (x-axis in bp). The red dots represent the case where the artificially added CpGs are included in the cytosine methylation calculation. The blue dots represent the case when they are excluded. Significantly improved auto-correlation is observed after artificial Cs are removed