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. 2016 Jan-Mar;17(1):17–25.

Table 4.

Multiple regression analyses of testosterone, oestradiol and oestradiol testosterone ratio in control, metabolic syndrome and type 2 diabetes mellitus groups

Groups Dependent parameter Predictors Regression coefficient P-value
Control R2=0.626, F=41.888, p=0<0.001 Testosterone
Oestradiol 0.780 0<0.001
ETR −0.832 0<0.001
R2=0.666, F=49.949, p=0<0.001 Oestradiol
Testosterone 0.696 0<0.001
ETR 0.816 0<0.001
R2=0.689, F=55.503, p=0<0.001 ETR
Testosterone −0.691 0<0.001
Oestradiol 0.760 0<0.001

Metabolic syndrome R2=0.515, F= 4.602, p=0.021 Testosterone
ETR −0.505 0.043
Triglyceride −0.129 0.601
Hip circumference −0.243 0.299
R2=0.625, F=4.995, p=0.013 Oestradiol
ETR 0.300 0.253
Triglyceride 0.253 0.251
Waist hip ratio −0.262 0.242
Diastolic blood pressure −0.324 0.111
R2=0.769, F=4.271, p=0.024 ETR
Oestradiol 0.598 0.083
Age −0.158 0.520
Fasting plasma glucose −0.129 0.655
Triglyceride −0.161 0.560
LDLC 0.157 0.479
Waist hip ratio −0.006 0.786
Testosterone −0.576 0.035

Type 2 diabetes mellitus R2=0.235, F=4.749, p=0.016 Testosterone
ETR −0.371 0.030
Prolactin 0.226 0.176
R2=0.325, F=15.406, p<0.001 Oestradiol ETR 0.570 0<0.001
R2=0.487, F=6.420, p=0.001 ETR
Oestradiol 0.503 0.001
Waist height ratio −0.035 0.938
Waist circumference 0.053 0.902
Waist hip ratio 0.388 0.02

ETR=Oestradiol Testosterone Ratio, LDLC=Low Density Lipoprotein Cholesterol