Table 1. Differences in Prognostic Factors Between Patients With Early and Advanced Cancer.
Early Stage | Advanced Stage | |
---|---|---|
Prognosis | Years, decades | Months, weeks, days |
Inception cohort | Cancer site specific Time of diagnosis Time of consultation |
All cancer groups Admission/referral to palliative care or hospice |
Prognostic factors |
Clinical: stage, laboratory studies Pathological: histology, grade Molecular: gene, microarray Others: treatments, resources |
Clinical: symptoms, laboratory studies Pathological: NA Molecular: NA Others: treatments, resources |
Tools | Scores: IPI Programs: Adjuvant online |
Scores: PaP, PPI Programs: PPS |
Implications | Overall outlook on life span Worse prognosis = more intensive cancer treatment New cancer treatment → changes in prognostic factors |
End-of-life planning Worse prognosis → limit cancer treatment Limited cancer treatment → same prognostic factors |
IPI = International Prognostic Index, NA = not applicable, PaP = Palliative Prognostic Score, PPI = Palliative Prognostic Index, PPS = Palliative Performance Scale.