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. Author manuscript; available in PMC: 2016 Feb 28.
Published in final edited form as: Nat Rev Nephrol. 2011 Dec 6;8(2):89–99. doi: 10.1038/nrneph.2011.189

Figure 1.

Figure 1

An additive genetic model for GFR. In this additive model, each copy of the G allele is associated with an increase in GFR. The β-coefficient (β) indicates the unit increase in GFR (a continuous trait) per copy of the G allele. The blue circles represent individual GFR estimates for individuals with the genotype indicated on the x-axis. The red line indicates the regression slope of GFR on genotype. Abbreviation: GFR, glomerular filtration rate.