Longitudinal changes of plasma lipids in relation to pubertal stages. A, ■, males; ●, females; B, C, and D, ◆, nonblack males; ■, black males; ▲, nonblack females; ●, black females; and E, ◆, nonblack; ■, black. All data points are least squares means ± SE at each pubertal stage. Lines connecting any pair of data points (vertical or horizontal) indicate significant differences (P < .0001).