Table II.
Outcomes by group
| Variable | Overall N=3082 |
Human milk on 0% of enteral feeding days N=659 |
Human milk on 1– 50% of enteral feeding days N=766 |
Human milk on 51– 99% of enteral feeding days N=725 |
Human milk on 100% of enteral feeding days N=932 |
P |
|---|---|---|---|---|---|---|
| Days from first feed to discharge or death | <0.01 | |||||
| <8 | 179 (5.8%) | 45 (6.8%) | 20 (2.2%) | 16 (2.2%) | 98 (10%) | |
| 8–14 | 949 (31%) | 166 (25%) | 140 (18%) | 187 (28%) | 456 (49%) | |
| 15–21 | 629 (20%) | 121 (18%) | 95 (12%) | 187 (26%) | 226 (24%) | |
| >21 | 1325 (43%) | 327 (50%) | 511 (67%) | 335 (46%) | 152 (16%) | |
| Days infant not fed after 1st feed | 3 (0, 13) | 4 (0, 16) | 12 (3, 27) | 3 (0, 13) | 0 (0, 4) | <0.01 |
| Weight gain from birth to discharge (g/d) | 19 (14, 24) | 20 (14, 26) | 20 (16, 25) | 19 (14, 24) | 17 (11, 22) | <0.01 |
| Positive blood culture after first feed | c318 (10%) | 78 (12%) | 138 (18%) | 70 (10%) | 32 (3.4%) | <0.01 |
| Percent of days on ventilator after 1st feed | <0.01 | |||||
| <25% | 1317 (43%) | 290 (45%) | 302 (40%) | 277 (39%) | 448 (48%) | |
| 25–49% | 920 (30%) | 203 (31%) | 230 (31%) | 205 (29%) | 282 (30%) | |
| 50–100% | 803 (26%) | 155 (24%) | 221 (29%) | 228 (32%) | 199 (21%) | |
| Percent of days on inotrope after 1st feed | 0.02 | |||||
| <25% | 2838 (93%) | 604 (93%) | 695 (92%) | 655 (92%) | 844 (95%) | |
| 25–49% | 145 (4.8%) | 25 (3.9%) | 45 (6.0%) | 38 (5.4%) | 37 (4.0%) | |
| 50–100% | 57 (1.9%) | 19 (2.9%) | 13 (1.7%) | 17 (2.4%) | 8 (0.9%) | |
| Necrotizing Enterocolitis | 1 (0.0%) | 1 (0.2%) | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | 0.30 |
| Mortality | 31 (1.1%) | 16 (2.6%) | 5 (0.7%) | 6 (0.9%) | 4 (0.4%) | <0.01 |