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. 2015 Dec 17;27(3):532–539. doi: 10.1093/annonc/mdv613

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© The Author 2015. Published by Oxford University Press on behalf of the European Society for Medical Oncology.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited

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Figure 1. — Study design. (A) Operative specimens from women undergoing surgery for HGSOC were sampled with a scalpel to acquire three surgical tumour samples and a 16G needle was used to obtain three mock biopsies. Matched surgical and biopsy samples from each case, with matched control tissue, were processed in parallel with fixation in NBF or UMFIX, or SF before downstream analysis. (B) Sample workflow: numbers of patients (P) and samples (S) used for analysis. Bx, biopsy; Tu, surgical tumour fragment; Ctrl, control tissue.