Figure 1. Presence of dendritic cells (DCs) in mouse cardiac valve. Mitral valve from a CD11c-EYFP transgenic mouse was whole-mount immunostained with MHCII antibody. The CD11c⁺ MHCII⁺ DCs were then visualized (green, CD11c; red, MHCII). CD11c⁺ MHCII⁺ DCs are also present in other cardiac valves (aortic, tricuspid, and pulmonary; data not shown). Scale bars, 20 µm.