Fig. 2. Effect of the penicillin G sodium salt pretreatment (6,000, 20,000 U/kg, for 5 days) on delayed hippocampal neuronal death after transient global forebrain ischemia in mice.

(A) Representative images of cresyl violet-stained brain coronal sections 3 days after transient forebrain ischemia or sham manipulation. The penicillin G sodium salt did not protect the medial CA1 pyramidal cells of the hippocampus 3 days after ischemia/reperfusion. The scale bars in e and f indicate 200 µm and 20 µm, respectively. (B) Quantitative analysis of the neuronal damage in the saline- and ampicillin-treated groups. There was no significant difference in neuronal damage between the saline- and penicillin G-treated groups.