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Presented is a simplified model for glucobrassicin digestion. I3C is freed from glucobrassicin by the mastication-released enzyme myrosinase. Gastric HCl drives dimerization of I3C to 3,3′-diindolylmethane, as well as other indole complexes that are released to the duodenum and distal digestive tract. I3C: Indole-3-Carbinol.
