Table 2.
Univariate and multivariate analyses for predictors of overall survival
| Total | 5-yr survival (%) | Median survival (mo) | Univariate analysis P | HR | 95%CI | Multivariate analysis P | |
| Overall | 158 | 59.7 | - | - | |||
| Age (≥ 60 yr) | - | - | - | 0.133 | |||
| Gender | - | - | 0.097 | ||||
| Male | 122 | 61.5 | 0.88 | 0.45-1.74 | 0.714 | ||
| Female | 36 | 55.4 | - | ||||
| BMI (≥ 28) | 0.080 | ||||||
| Yes | 37 | 48.2 | 46 | 1.55 | 0.81-2.98 | 0.186 | |
| No | 113 | 63.6 | - | ||||
| Pre-op AFP (≥ 100 ng/dL) | 0.087 | ||||||
| Yes | 19 | 51.8 | - | 1.50 | 0.68-3.32 | 0.316 | |
| No | 129 | 60.8 | - | ||||
| Cirrhosis | - | - | - | 0.950 | |||
| Alcohol related | 0.048 | ||||||
| Yes | 22 | 86.4 | - | 0.30 | 0.09-1 | 0.051 | |
| No | 131 | 55.5 | - | ||||
| Hepatitis B infection | - | - | - | 0.156 | |||
| Hepatitis C infection | - | - | - | 0.130 | |||
| Others | - | - | - | 0.281 | |||
| Blood type | - | - | - | 0.470 | |||
| Rhesus | - | - | - | 0.554 | |||
| Radiofrequency | - | - | - | 0.821 | |||
| MELD (≥ 15) | - | - | - | 0.721 | |||
| Chemo-embolization | - | - | - | 0.877 | |||
| Tumor alcoholization | - | - | - | 0.118 | |||
| Graft/body % (≥ 2) | - | - | - | 0.163 | |||
| No. of lesions (> 3) | - | - | - | 0.819 | |||
| Largest lesion (≥ 30 mm) | - | - | - | 0.640 | |||
| Edmond-Steiner degree | 0.013 | ||||||
| III-IV | 88 | 48.9 | 51 | 2.19 | 1.07-4.47 | 0.031 | |
| 0-II | 59 | 74.4 | - | ||||
| Vascular invasion | - | - | - | 0.290 | |||
| Microsatellite lesions | - | - | - | 0.283 | |||
| Cholangiocarcinoma | - | - | - | 0.957 | |||
| IBS | 0.510 | ||||||
| Yes | 122 | 59.5 | - | 1.56 | 0.74-3.30 | 0.237 | |
| No | 36 | 64.5 | - | ||||
BMI: Body mass index; AFP: Alpha-feto protein; IBS: Intraoperative blood salvage; MELD: Model of End-Stage Liver Disease. The number of patients included in multivariate model is 141.