Table 1. The 40 most highly expressed miRNAs in the human retina.

Rank	Exactly matching the annotated sequence		Including isomiRs
	miRNA Name	Mean Expression1	miRNA Name	Mean Expression1	Rank variation2	Variation in reads (%)3
1	hsa-miR-182-5p	304344	hsa-miR-182-5p	310414	-	+2
2	hsa-miR-183-5p	131095	hsa-miR-183-5p	177857	-	+36
3	hsa-miR-26a-5p	108111	hsa-miR-181a-5p	104145	+1	+11
4	hsa-miR-181a-5p	94166	hsa-miR-26a-5p	54470	-1	-50
5	hsa-miR-204-5p	64600	hsa-miR-204-5p	37292	-	-42
6	hsa-miR-22-3p	39597	hsa-miR-30a-5p	26149	New entry	+1617
7	hsa-let-7a-5p	22123	hsa-miR-22-3p	19998	-1	-49
8	hsa-miR-191-5p	21971	hsa-miR-30d-5p	18513	+24	+619
9	hsa-miR-124-3p	16883	hsa-miR-124-3p	18105	+1	+7
10	hsa-miR-9-5p	17074	hsa-let-7a-5p	14516	-3	-34
11	hsa-miR-127-3p	12907	hsa-miR-9-5p	14355	-1	-16
12	hsa-miR-192-5p	12726	hsa-miR-143-3p	14389	+12	+284
13	hsa-let-7f-5p	11418	hsa-miR-27b-3p	13769	+1	+45
14	hsa-miR-27b-3p	9497	hsa-miR-191-5p	13035	-6	-41
15	hsa-miR-96-5p	7380	hsa-miR-127-3p	10488	-4	-19
16	hsa-miR-26b-5p	6399	hsa-miR-101-3p	9660	New entry	+721
17	hsa-miR-30b-5p	5196	hsa-miR-192-5p	9464	-5	-26
18	hsa-miR-92a-3p	5251	hsa-miR-125a-5p	8437	+11	+197
19	hsa-miR-99b-5p	5556	hsa-let-7f-5p	8237	-6	-28
20	hsa-miR-125b-5p	4571	hsa-miR-96-5p	7776	-5	+5
21	hsa-miR-151a-5p	4536	hsa-miR-99b-5p	7344	-2	+32
22	hsa-miR-211-5p	4452	hsa-miR-92a-3p	6798	-4	+29
23	hsa-miR-126-5p	3792	hsa-miR-181b-5p	5317	+5	+73
24	hsa-miR-143-3p	3748	hsa-miR-30e-5p	4137	New entry	+1918
25	hsa-miR-16-5p	3562	hsa-miR-125b-5p	3830	-5	-16
26	hsa-let-7g-5p	3317	hsa-miR-100-5p	3550	+8	+16
27	hsa-miR-148a-3p	3066	hsa-miR-30b-5p	2792	-10	-46
28	hsa-miR-181b-5p	3078	hsa-miR-26b-5p	2714	-12	-58
29	hsa-miR-125a-5p	2837	hsa-miR-181c-5p	2770	+3	+2
30	hsa-miR-92b-3p	3029	hsa-miR-151a-5p	2777	-9	+4
31	hsa-miR-181a-2-3p	2664	hsa-miR-151a-3p	2528	+7	-7
32	hsa-miR-181c-5p	2707	hsa-miR-148a-3p	2522	-5	-18
33	hsa-miR-30d-5p	2574	hsa-miR-16-5p	2444	-8	-31
34	hsa-miR-100-5p	2285	hsa-miR-92b-3p	2556	-4	-16
35	hsa-let-7c-5p	2125	hsa-miR-211-5p	2421	-13	+23
36	hsa-miR-103a-3p	1968	hsa-let-7g-5p	2356	-10	-29
37	hsa-miR-29b-3p	1833	hsa-miR-486-5p	2316	New entry	+44
38	hsa-miR-151a-3p	1732	hsa-miR-29a-3p	2193	New entry	+86
39	hsa-miR-186-5p	1750	hsa-miR-126-5p	2075	-16	-45
40	hsa-miR-21-5p	1729	hsa-miR-30c-5p	2005	New entry	+93

¹TMM normalization.

²Variation in the ranking of each miRNA following isomiR inclusion.

³Variation in the mean expression values (shown as % of reads).