Supplemental Figure 2.

Integration of ATAC-seq data with histone epigenetic ChIP-seq, and FAIRE-seq data for known α- and β-cell genes. Pooled sequencing tracks for the (A) DPP4, (B) MAFA, (C) NEUROD1 and PAX6 (D) loci from α-cell, β-cell, and acinar cell ATAC-seq data (blue); α-cell and β-cell H3K4me3 (green) and H3K4me27 (red) ChIP-seq data; whole islet H2A.Z ChIP-seq data (light blue); and whole islet FAIRE-seq data (pink). Cell type-selective peaks are identified in blue below RefSeq Genes, followed by islet transcription factor ChIP-seq peaks in purple. Known promoter regions are indicated with black arrows, and putative enhancer regions are indicated with orange arrows.