Figure 7.

Exercise and endurance capacity. (A) Maximal velocity. (B) Maximal workload as assessed via an incremental exercise protocol. (C) Endurance capacity as estimated from time to exhaustion in a low intensity exercise protocol. (D) Workload performed in a high-intensity exercise protocol (75–80% VO₂ max). (E) Pre- and post-exercise blood glucose levels. (F) Glucose Excursion curve. (G) Area Under Curve (AUC) from glucose excursion curve following a pre- and post-exercise conscious IPGTT (2 g/kg of glucose, 6 h fast) over 120 min. (H) Pre-post exercise plasma lactate after a 6 h fasting period from control and gys1-KO mice at 22 weeks of age. Data shown are mean ± SEM (*p < 0.05 **p < 0.01 vs. control mice, n = 14–16 per group).