Table 3. Clinical characteristics of coronary artery disease patients with EF <50% or ≥50%.
Variables | Without AMI (n = 4893) | Pvalue | With AMI (n = 1045) | Pvalue | ||
---|---|---|---|---|---|---|
— | LVEF ≥50% (n = 4591) | LVEF <50% (n = 302) | — | LVEF ≥50% (n = 916) | LVEF <50% (n = 129) | — |
Age, yrs | 65.2 ± 10.1 | 66.2 ± 10.5 | 0.099 | 63.6 ± 11.6 | 69.7 ± 12.3 | <0.001 |
Men (n,%) | 3274(71.3%) | 248(82.1%) | <0.001 | 733(80.0%) | 97(75.2%) | 0.204 |
BMI (kg/m2) | 24.7 ± 1.41 | 24.7 ± 1.43 | 0.823 | 24.8 ± 1.47 | 24.6 ± 1.53 | 0.294 |
Current smoking (n,%) | 937(20.4%) | 63(20.9%) | 0.851 | 312(34.1%) | 34(26.4%) | 0.082 |
Diabetes mellitus (n,%) | 1596(34.8%) | 137(45.4%) | <0.001 | 301(32.9%) | 65(50.4%) | <0.001 |
Hypertension (n,%) | 3138(68.4%) | 188(62.3%) | 0.028 | 565(61.7%) | 81(62.8%) | 0.808 |
SBP (mmHg) | 135 ± 21.3 | 133 ± 19.4 | 0.130 | 134 ± 20.1 | 131 ± 21.4 | 0.111 |
DBP (mmHg) | 75.5 ± 11.9 | 75.4 ± 12.1 | 0.887 | 75.5 ± 11.3 | 74.1 ± 12.6 | 0.206 |
LVEF (%) | 65.2 ± 5.36 | 41.7 ± 5.93 | <0.001 | 61.2 ± 5.91 | 43.8 ± 5.20 | <0.001 |
Cardiac troponin I (ng/ml) | 0.01(0.01–0.01) | 0.02(0.01–0.04) | <0.001 | 4.99(1.13–20.9) | 6.66(1.29–38.0) | 0.066 |
Serum creatinine (umol/l) | 78(67–90) | 86(71–97) | <0.001 | 79(68–90) | 89(72–103) | <0.001 |
eGFR (ml/min/1.73 m2) | 90.2 ± 19.6 | 83.7 ± 24.2 | <0.001 | 92.2 ± 20.9 | 78.9 ± 24.3 | <0.001 |
Serum calcium (mmol/l) | 2.20 ± 0.10 | 2.19 ± 0.11 | 0.024 | 2.11 ± 0.12 | 2.07 ± 0.12 | <0.001 |
Serum phosphate (mmol/l) | 1.16 ± 0.20 | 1.16 ± 0.23 | 0.947 | 1.09 ± 0.30 | 1.11 ± 0.34 | 0.647 |
Total cholesterol (mmol/l) | 3.94 ± 1.05 | 3.98 ± 1.22 | 0.604 | 4.35 ± 1.08 | 4.14 ± 0.96 | 0.038 |
Total triglyceride (mmol/l) | 1.74 ± 1.20 | 1.60 ± 1.02 | 0.040 | 1.74 ± 1.16 | 1.48 ± 0.89 | 0.022 |
LDL-C (mmol/l) | 2.31 ± 0.85 | 2.39 ± 0.99 | 0.146 | 2.69 ± 0.87 | 2.50 ± 0.80 | 0.026 |
HDL-C (mmol/l) | 1.09 ± 0.28 | 1.04 ± 0.27 | 0.005 | 1.02 ± 0.26 | 1.06 ± 0.30 | 0.170 |
Fasting plasma glucose (mmol/l) | 5.49 ± 1.63 | 5.82 ± 2.12 | 0.001 | 6.18 ± 2.38 | 6.87 ± 2.94 | 0.004 |
AMI: acute myocardial infarction; LVEF: left ventricular ejection fraction; BMI: body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; LDL-C: low-density lipoprotein cholesterol; HDL-C: high-density lipoprotein cholesterol; eGFR: estimated glomerular filtration rate. Values are means ± SD, medians (interquartile range), or numbers with percentage in parenthesis.