Figure 5. Pertubations of identified sugar phosphates in A. baumannii.

Pentose phosphate pathway (PPP) of A. baumannii. PPP intermediates showed significant differences between polymyxin-resistant and polymyxin-susceptible A. baumannii strains. Metabolites in the red bold box indicate metabolites that were at least 2-fold more abundant in polymyxin-resistant 16906R strain than polymyxin-susceptible ATCC 19606 strain. Metabolites in the red box indicate metabolites that were less than 2-fold more abundant in the 19606R strain. The blue bold box indicates the metabolite that was at least 2-fold less abundant in 16906R than ATCC 19606. The blue box indicates the metabolite that was less than 2-fold less abundant in the 03–149.2 polymyxin-resistant strain than polymyxin-susceptible 03–149.1 strain. The black boxes indicate metabolites that were not detected. *p < 0.05; **p < 0.01.