Figure 5. Measure of membrane resistence of Xenopus oocytes.

Ramp (from −85 to + 55 mV) protocols (A) were applied in non transfected oocytes starting from the holding potential of −25 mV. Representative currents elicited by the protocol in not-exposed oocytes (black line in B), exposed to Co₃O₄ NP suspensions (red line in C) and perfused with ionophore A23187 (blue line in D). Current mean values at −80, −60, −40, −20, 0 and +20 mV (± SE) obtained from at least 12 oocytes (from 2 different batches) are plotted in (E).