Table 1.
Patient and tumor characteristics of included cohorts
| Characteristic | Discovery cohort (n) | Validation cohort (n) |
|---|---|---|
| Total number of samples | 188 | 669 |
| Unique patients | 181 | 666 |
| Primary tumors | 183 | 665 |
| Recurrent tumors | 5 | 4 |
| Median age, years | 48 | 58 |
| Estrogen receptor status | ||
| Positive | 97 | 474 |
| Negative | 77 | 142 |
| Tumor size | ||
| T1 | 66 | 176 |
| T2 | 81 | 371 |
| T3 | 5 | 86 |
| Node status | ||
| Positive | 59 | 356 |
| Negative | 91 | 290 |
| Histological type | ||
| Ductal | 120 | 446 |
| Lobular | 8 | 134 |
| Medullary | 3 | 5 |
| Mixed | 9 | 24 |
| Other | 18 | 44 |
| Molecular subtype | ||
| Luminal A | 41 | 251 |
| Luminal B | 30 | 144 |
| HER2-enriched | 32 | 73 |
| Basal-like | 44 | 126 |
| Normal-like | 11 | 67 |
HER2 human epidermal growth factor receptor 2