A. Black Women (n=29): Women homozygous for GNB3 TT (black bars) compared to women carrying the C allele (heterozygous subjects and women homozygous for the C allele combined, gray bars). Significantly lower LVEF for GNB3 TT subjects at entry (p value=0.04), which increases to 14 EF units by 12 months (p=0.02).
B. White women (n=63): Women homozygous for GNB3 TT (black bars) with subjects carrying the C allele (gray bars). No significant difference in LVEF at entry (p value=0.04), but a significantly lower LVEF in women with the GNB3 TT genotype by 12 months (p=0.04).