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. Author manuscript; available in PMC: 2017 Mar 1.
Published in final edited form as: Circ Heart Fail. 2016 Mar;9(3):e002683. doi: 10.1161/CIRCHEARTFAILURE.115.002683

TABLE.

Clinical Characteristics by GNB3 Genotype

All
(N=97)
TT
(N=22)
TC+CC
(N=75)
p value*
Age (years) 30 ± 6 28 ± 7 30 ± 6 0.15
Gravida 2 (1,4) 2.5 (1,4) 2 (1,4) 0.93
Para 2 (1,3) 3 (1,3) 2 (1,3) 0.38
Race, % Black 30 68 19 <0.001
Days post-Partum 24 (11,51) 34.5 (14,63) 24 (10,49) 0.17
BMI 29 ± 7 30 ± 7 29 ± 8 0.42
NYHA Class (% I/II/III/IV) 12/45/25/18 18/27/36/18 11/51/21/17 0.22
HR 86 ± 16 86 ± 15 86 ± 17 0.94
BP systolic 112 ± 17 115 ± 19 111 ± 17 0.35
BP diastolic 70 ± 13 73 ± 13 69 ± 13 0.20
ACE Inhibitor (%) 81 91 79 0.16
Aldosterone receptor antagonist 27 32 25 0.36
Beta Blocker (%) 89 96 87 0.23

Comparison of women with the GNB3 TT genotype to those with the GNB3 C allele. BMI=body mass index, HR = heart rate, BP= blood pressure, NYHA=New York Heart Association, ACE=angiotensin converting enzyme. For gravida, para and days post-partum values listed are the median (with 25th and 75th percentiles). All other values are mean and standard deviation. There was a significantly higher percentage of black women in the subset with the GNB3 TT genotype (68%) than in the subset with the C allele (19%), p<0.001. No other significant differences.