TABLE.
All (N=97) |
TT (N=22) |
TC+CC (N=75) |
p value* | |
---|---|---|---|---|
Age (years) | 30 ± 6 | 28 ± 7 | 30 ± 6 | 0.15 |
Gravida | 2 (1,4) | 2.5 (1,4) | 2 (1,4) | 0.93 |
Para | 2 (1,3) | 3 (1,3) | 2 (1,3) | 0.38 |
Race, % Black | 30 | 68 | 19 | <0.001 |
Days post-Partum | 24 (11,51) | 34.5 (14,63) | 24 (10,49) | 0.17 |
BMI | 29 ± 7 | 30 ± 7 | 29 ± 8 | 0.42 |
NYHA Class (% I/II/III/IV) | 12/45/25/18 | 18/27/36/18 | 11/51/21/17 | 0.22 |
HR | 86 ± 16 | 86 ± 15 | 86 ± 17 | 0.94 |
BP systolic | 112 ± 17 | 115 ± 19 | 111 ± 17 | 0.35 |
BP diastolic | 70 ± 13 | 73 ± 13 | 69 ± 13 | 0.20 |
ACE Inhibitor (%) | 81 | 91 | 79 | 0.16 |
Aldosterone receptor antagonist | 27 | 32 | 25 | 0.36 |
Beta Blocker (%) | 89 | 96 | 87 | 0.23 |
Comparison of women with the GNB3 TT genotype to those with the GNB3 C allele. BMI=body mass index, HR = heart rate, BP= blood pressure, NYHA=New York Heart Association, ACE=angiotensin converting enzyme. For gravida, para and days post-partum values listed are the median (with 25th and 75th percentiles). All other values are mean and standard deviation. There was a significantly higher percentage of black women in the subset with the GNB3 TT genotype (68%) than in the subset with the C allele (19%), p<0.001. No other significant differences.