Table 6.
Clinical outcomes following BTK interventions in patients with CLI according to blood pressure control at 12 months
| Variable. n% | Total (n = 165 Pts) (n = 201 Limb) (n = 246 Lesion) | Controlled HTN (n = 53 Pts) (n = 66 Limb) (n = 90 Lesion) | Uncontrolled HTN (n = 112 Pts) (n = 135 Limb) (n = 156 Lesion) | P Value |
|---|---|---|---|---|
| 12-months clinical outcomes | ||||
| Mortality | 9 (5.4) | 2 (3.7) | 7 (6.2) | 0.720 |
| Cardiac death | 5 (3.0) | 1 (1.8) | 4 (3.5) | 1.000 |
| TLR, Pts | 18 (10.9) | 6 (11.3) | 12 (10.7) | 0.907 |
| TLR, Limb | 21 (10.4) | 6 (9) | 15 (11.1) | 0.808 |
| TER, Pts | 20 (12.1) | 7 (13.2) | 13 (11.6) | 0.769 |
| TER, Limb | 25 (12.4) | 7 (10.6) | 18 (13.3) | 0.655 |
| Non TER | 7 (4.2) | 3 (5.7) | 4 (3.6) | 0.534 |
| Amputations - Pts | 40 (24.2) | 18 (33.9) | 22 (19.6) | 0.045 |
| Amputations - Limb | 41 (20.3) | 19 (28.7) | 22 (16.2) | 0.061 |
| Major | ||||
| above the knee | 0 (0.0) | 0 (0.0) | 0 (0.0) | 1.000 |
| above the ankle - Pts | 10 (6.0) | 7 (13.2) | 3 (2.6) | 0.013 |
| above the ankle - Limb | 10 (4.9) | 7 (10.6) | 3 (2.2) | 0.016 |
| minor (below the ankle) - Pts | 30 (18.1) | 11 (20.7) | 19 (16.9) | 0.556 |
| minor (below the ankle) - Limb | 31 (15.4) | 12 (18.1) | 19 (14) | 0.533 |
| Myocardial infarction | 2 (1.2) | 1 (1.8) | 1 (0.8) | 0.541 |
| PTCA | 7 (4.2) | 3 (5.6) | 4 (3.5) | 0.682 |
| Cerebrovascular accidents | 1 (0.6) | 0 (0.0) | 1 (0.8) | 1.000 |
| Limb salvage | 147/156 (94.2) | 45/51 (88.2) | 102/105 (97.1) | 0.059 |
| Angiogram to follow-up | 55 (33.3) | 18 (33.9) | 37 (33) | 0.906 |
| CT | 21 (38.1) | 8 (44.4) | 13 (35.1) | 0.505 |
| PAG | 42 (76.3) | 13 (72.2) | 29 (78.3) | 0.738 |
| Binary restenosis | 35 (63.6) | 11 (61.1) | 24 (64.8) | 0.786 |
| Total re-occlusion | 29 (52.7) | 8 (44.4) | 21 (56.7) | 0.391 |
| Primary patency | 20 (36.3) | 7 (38.8) | 13 (35.1) | 0.786 |
| Secondary patency | 39 (70.9) | 11 (61.1) | 28 (75.6) | 0.264 |
| Non-Total occlusion; Runoff (≥1) included Collateral, to distal | 53 (96.3) | 17 (94.4) | 36 (97.2) | 1.000 |
Values are mean ± SD (range). BTK indicates Below-the-knee artery, CLI critical limb ischemia, HTN hypertension, Pts patients, TLR target lesion revascularization, TER target extremity revascularization, PTCA percutaneous transluminal coronary angioplasty, CT computed tomography, PAG follow-up invasive peripheral angiography