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. Author manuscript; available in PMC: 2017 Feb 1.
Published in final edited form as: Circ Cardiovasc Qual Outcomes. 2016 Feb;9(2 Suppl 1):S70–S76. doi: 10.1161/CIRCOUTCOMES.115.002461

Table 3.

MRI Measures of Study participants by a History of Normotensive or Hypertensive Pregnancy Disorders

MRI Characteristics Normotensive Pregnancy (n = 796) Hypertensive Pregnancy (n = 176)

Non-adjusted Model 1 Model 2 Non-adjusted Model 1 Model 2
Total intracranial
volume
1355
(1347-1363)
/ / 1360
(1344-1376)
/ /
Ventricle volume 21.0
(20.2-21.9)
20.7
(20.0-21.5)
20.8
(20.0-21.6)
18.8
(17.4-20.2)
20.3
(18.6-21.9)
19.9
(18.1-21.6)
Brain atrophy 287
(282-291)
286
(282-290)
285
(281-289)
293
(284-301)
297a
(288-305)
296a
(287-305)
White matter
lesion volume
8.3
(7.8-8.8)
8.1
(7.7-8.6)
8.2
(7.7-8.7)
8.0
(6.8-9.3)
8.9
(7.9-9.9)
8.3
(7.3-9.5)

Values shown are mean with 95% confidence interval for mean.

The model for total intracranial volume is univariate.

Model 1 adjusted for age, BMI, smoking, hypertension, family history of hypertension, total intracranial volume, and accounted for familial clustering.

Model 2 adjusted for all variables from Model 1 plus duration of hypertension.

a

Significant difference (P<0.05) compared to women with normotensive pregnancies.