Table 1. Origin and incidence of maternal aneuploidies.
Chromosome missegregation eventsd | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|
Dataset: | Mean maternal agea | nb | % aneuploid oocytes | All events | Aneuploid outcome in oocyte | Gain in oocyte | Loss in oocyte | Total chr | ||
MI | MII | MI | MII | |||||||
Oocyte-PB trios | 37.3 (33-41) | 13 | 62% | 26 | 12 | 2 | 4 | 4 | 2 | 299 |
Embryo-PB trios | 38.3 | 10 | 70% | 19 | 8 | 4 | 1 | 0 | 3 | 230 |
Embryo only | 37.1 (34-42) | 29c | 54% | n.d. | 19 | 5 | 4 | n.d | n.d. | 667 |
Mean age and range.
Number of trios or embryos analysed
28 embryos and 1 chorionic villus sample.
Statistical test for significance of MII nondisjunction rates in oocyte-PB and embryo-PB trios: 6 out of 299 compared to 4 out of 230, respectively, G-test with Williams’ correction, p = 0.82.
n.d., not determined since no information from polar bodies.