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. Author manuscript; available in PMC: 2016 Feb 29.
Published in final edited form as: Nat Genet. 2015 May 18;47(7):727–735. doi: 10.1038/ng.3306

Table 1. Origin and incidence of maternal aneuploidies.

Chromosome missegregation eventsd
Dataset: Mean maternal agea nb % aneuploid oocytes All events Aneuploid outcome in oocyte Gain in oocyte Loss in oocyte Total chr
MI MII MI MII
Oocyte-PB trios 37.3 (33-41) 13 62% 26 12 2 4 4 2 299
Embryo-PB trios 38.3 10 70% 19 8 4 1 0 3 230
Embryo only 37.1 (34-42) 29c 54% n.d. 19 5 4 n.d n.d. 667
a

Mean age and range.

b

Number of trios or embryos analysed

c

28 embryos and 1 chorionic villus sample.

d

Statistical test for significance of MII nondisjunction rates in oocyte-PB and embryo-PB trios: 6 out of 299 compared to 4 out of 230, respectively, G-test with Williams’ correction, p = 0.82.

n.d., not determined since no information from polar bodies.