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. 2016 Feb 29;14:57. doi: 10.1186/s12957-016-0815-7

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© Su et al. 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Pharmacological modulation of autophagy enhances overexpressed RBM5-induced apoptosis. A549 cells were treated with RBM5 overexpression (RBM5 group), control plasmids (control group), RBM5 overexpression combined with 3-MA (RBM5 + 3-MA group), or 3-MA alone (3-MA group). a Cell viability was examined by MTT assay. b Transfected A549 cells were treated with varying concentrations of cisplatin for 24 h. Cell viability was determined by MTT assay. Data were presented as mean ± SD for three replicate experiments. **P < 0.01, ***P < 0.001