Table 3.
Summary of the meta-analysis of the treatment effect between groups based on increments between baseline and end trial data presented by subgroup analysis based on periodontal diagnosis (see Additional file 1 for further details)
| Index # online supportive | ID# Selected studies | ‘Random/Fixed’ effect model | Periodontal diagnosis | Difference in means between groups (in mm) | 95 % confidence interval | p-value | Test for heterogeneity* | |
|---|---|---|---|---|---|---|---|---|
| Appendix | See Appendix S3 | Test for overall effect | p-value | I2 | ||||
| Mean PD* | ||||||||
| App. S52 | II,III,VI,VIII,XVI,XVII | Random | Aggressive Periodontitis | −0.48 | (−0.33; −0.63) | <0.00001 | 0.32 | 14 % |
| I,II,XIII | Chronic Periodontitis | −0.47 | (−0.32; −0.63) | <0.00001 | 0.71 | 0 % | ||
| NA | Unknown | NA | NA | NA | NA | NA | ||
| Mean CAL** | ||||||||
| App. S55 | II,III,VI,VIII,XVI,XVII | Random | Aggressive Periodontitis | +0.39 | (025; 0.53) | <0.00001 | 0.59 | 0 % |
| I, IX. XIII | Chronic Periodontitis | +0.32 | (0.16; 0.47) | <0.00001 | 0.64 | 0 % | ||
| XX | Unknown | +0.00 | (−0.35;0.35) | 1.00 | NA | NA | ||
* = test for subgroup analysis p = 0.96
** = test for subgroup analysis p = 0.12
NA = not applicable