Table 1. Clinical features and metastasis sites.
| Features | Liver metastasis (%) | P value* | Lung metastasis (%) | P value# | Bone metastasis (%) | P value& | Brain metastasis (%) | P value$ | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| No | Yes | No | Yes | No | Yes | No | Yes | |||||
| Sex | ||||||||||||
| Women | 18,802 (87.7) |
2,628 (12.3) |
<0.001 | 20,542 (96.1) |
823 (3.9) |
0.005 | 21,190 (99.3) |
160 (0.7) |
0.032 | 21,282 (99.7) |
54 (0.3) |
0.487 |
| Men | 20,162 (85.4) |
3,452 (14.6) |
22,492 (95.6) |
1,029 (4.4) |
23,291 (99.1) |
220 (0.9) |
23,456 (99.8) |
52 (0.2) |
||||
| Age | <0.001 | <0.001 | <0.001 | <0.001 | ||||||||
| Mean | 66.00 | 68.91 | 65.64 | 68.56 | 65.58 | 61.96 | 65.55 | 64.24 | ||||
| SD | 13.78 | 15.47 | 13.81 | 15.25 | 13.79 | 13.14 | 13.79 | 13.07. | ||||
| Median | 66 | 62 | 66 | 63 | 66 | 62 | 66 | 64 | ||||
| Ethnicity | <0.001 | <0.001 | 0.057 | 0.037 | ||||||||
| Caucasian | 30,615 (87.1) |
4,526 (12.9) |
33,652 (96.1) |
1,358 (3.9) |
34,720 (99.2) |
281 (0.8) |
34,900 (99.8) |
81 (0.2) |
||||
| African American | 4,362 (82.1) |
952 (17.9) |
5,015 (94.6) |
287 (5.4) |
5,237 (98.8) |
63 (1.2) |
5,288 (99.7) |
17 (0.3) |
||||
| Asian | 3,166 (86.7) |
487 (13.3) |
3,475 (95.3) |
171 (4.7) |
3,604 (99.3) |
27 (0.7) |
3,624 (99.9) |
5 (0.1) |
||||
| Other | 544 (84.1) |
103 (15.9) |
607 (95.0) |
32 (5.0) |
634 (98.9) |
7 (1.1) |
638 (99.5) |
3 (0.5) |
||||
| Unknown | 277 (95.8) |
12 (4.2) |
285 (98.6) |
4 (1.4) |
286 (99.3) |
2 (0.7) |
400 (99.8) |
1 (0.2) |
||||
| Primary tumor sites | <0.001 | <0.001 | <0.001 | 0.060 | ||||||||
| Right colon | 16,009 (87.5) |
2,284 (12.5) |
17,672 (96.9) |
562 (3.1) |
18,108 (99.3) |
120 (0.7) |
18,167 (99.7) |
55 (0.3) |
||||
| Left colon | 14307 (84.7) |
2581 (15.3) |
16,095 (95.6) |
741 (4.4) |
16,673 (99.1) |
146 (0.9) |
16,782 (99.8) |
33 (0.2) |
||||
| Rectal | 8,648 (87.7) |
1,215 (12.3) |
9,267 (94.4) |
549 (5.6) |
9,700 (98.8) |
114 (1.2) |
9,789 (99.8) |
18 (0.2) |
||||
| Grade | <0.001 | <0.001 | <0.001 | <0.001 | ||||||||
| Well | 3,518 (93.3) |
251 (0.7) |
3,679 (97.9) |
79 (2.1) |
3,747 (99.6) |
14 (0.4) |
3,759 (99.9) |
2 (0.1) |
||||
| Moderate | 25,867 (87.9) |
3,545 (12.1) |
28,268 (96.3) |
1,071 (3.7) |
29,123 (99.4) |
180 (0.6) |
29,236 (99.8) |
59 (0.2) |
||||
| Poorly | 5,383 (83.3) |
1,076 (16.7) |
6,154 (95.7) |
274 (4.3) |
6,357 (98.8) |
74 (1.2) |
6,395 (99.6) |
28 (0.4) |
||||
| Undifferentiated | 828 (84.4) |
153 (15.6) |
946 (96.5) |
34 (3.5) |
966 (98.6) |
14 (1.4) |
978 (99.9) |
1 (0.1) |
||||
| Unknown | 3,368 (76.1) |
1,055 (23.9) |
3,987 (91.0) |
394 (9.0) |
4,288 (97.8) |
98 (2.2) |
4,370 (99.6) |
16 (0.4) |
||||
| Insurance | <0.001 | <0.001 | 0.044 | 0.237 | ||||||||
| Insured | 36,682 (86.8) |
5,595 (13.2) |
40,430 (96.0) |
1,701 (4.0) |
41,752 (99.2) |
352 (0.8) |
41,991 (99.8) |
98 (0.2) |
||||
| Uninsured | 1,393 (79.9) |
350 (20.1) |
1,617 (93.1) |
120 (6.9) |
1,718 (98.7) |
23 (1.3) |
1,732 (99.6) |
7 (0.4) |
||||
| Unknown | 889 (86.8) |
135 (13.2) |
987 (97.0) |
31 (3.0) |
1,011 (99.5) |
5 (0.5) |
1,015 (99.9) |
1 (0.1) |
||||
| Marital status | <0.001 | <0.001 | 0.465 | 0.084 | ||||||||
| Married | 20,781 (87.0) |
3,116 (13.0) |
22,945 (96.3) |
876 (3.7) |
23,619 (99.2) |
192 (0.8) |
23,736 (99.8) |
58 (0.2) |
||||
| Unmarried | 15,769 (85.6) |
2,650 (14.4) |
17,477 (95.2) |
878 (4.8) |
18,169 (99.1) |
167 (0.9) |
18,290 (99.7) |
47 (0.3) |
||||
| Unknown | 2,414 (88.5) |
314 (11.5) |
2,612 (96.4) |
98 (3.6) |
2,693 (99.2) |
21 (0.8) |
2,712 (99.9) |
1 (0.1) |
||||
SD: Standard deviation.
*
The comparison between patients with and without liver metastasis.
#
The comparison between patients with and without lung metastasis.
&
The comparison between patients with and without bone metastasis.
$
The comparison between patients with and without brain metastasis.