Table 1. Clinical features and metastasis sites.
Features | Liver metastasis (%) | P value* | Lung metastasis (%) | P value# | Bone metastasis (%) | P value& | Brain metastasis (%) | P value$ | ||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
No | Yes | No | Yes | No | Yes | No | Yes | |||||
Sex | ||||||||||||
Women | 18,802 (87.7) |
2,628 (12.3) |
<0.001 | 20,542 (96.1) |
823 (3.9) |
0.005 | 21,190 (99.3) |
160 (0.7) |
0.032 | 21,282 (99.7) |
54 (0.3) |
0.487 |
Men | 20,162 (85.4) |
3,452 (14.6) |
22,492 (95.6) |
1,029 (4.4) |
23,291 (99.1) |
220 (0.9) |
23,456 (99.8) |
52 (0.2) |
||||
Age | <0.001 | <0.001 | <0.001 | <0.001 | ||||||||
Mean | 66.00 | 68.91 | 65.64 | 68.56 | 65.58 | 61.96 | 65.55 | 64.24 | ||||
SD | 13.78 | 15.47 | 13.81 | 15.25 | 13.79 | 13.14 | 13.79 | 13.07. | ||||
Median | 66 | 62 | 66 | 63 | 66 | 62 | 66 | 64 | ||||
Ethnicity | <0.001 | <0.001 | 0.057 | 0.037 | ||||||||
Caucasian | 30,615 (87.1) |
4,526 (12.9) |
33,652 (96.1) |
1,358 (3.9) |
34,720 (99.2) |
281 (0.8) |
34,900 (99.8) |
81 (0.2) |
||||
African American | 4,362 (82.1) |
952 (17.9) |
5,015 (94.6) |
287 (5.4) |
5,237 (98.8) |
63 (1.2) |
5,288 (99.7) |
17 (0.3) |
||||
Asian | 3,166 (86.7) |
487 (13.3) |
3,475 (95.3) |
171 (4.7) |
3,604 (99.3) |
27 (0.7) |
3,624 (99.9) |
5 (0.1) |
||||
Other | 544 (84.1) |
103 (15.9) |
607 (95.0) |
32 (5.0) |
634 (98.9) |
7 (1.1) |
638 (99.5) |
3 (0.5) |
||||
Unknown | 277 (95.8) |
12 (4.2) |
285 (98.6) |
4 (1.4) |
286 (99.3) |
2 (0.7) |
400 (99.8) |
1 (0.2) |
||||
Primary tumor sites | <0.001 | <0.001 | <0.001 | 0.060 | ||||||||
Right colon | 16,009 (87.5) |
2,284 (12.5) |
17,672 (96.9) |
562 (3.1) |
18,108 (99.3) |
120 (0.7) |
18,167 (99.7) |
55 (0.3) |
||||
Left colon | 14307 (84.7) |
2581 (15.3) |
16,095 (95.6) |
741 (4.4) |
16,673 (99.1) |
146 (0.9) |
16,782 (99.8) |
33 (0.2) |
||||
Rectal | 8,648 (87.7) |
1,215 (12.3) |
9,267 (94.4) |
549 (5.6) |
9,700 (98.8) |
114 (1.2) |
9,789 (99.8) |
18 (0.2) |
||||
Grade | <0.001 | <0.001 | <0.001 | <0.001 | ||||||||
Well | 3,518 (93.3) |
251 (0.7) |
3,679 (97.9) |
79 (2.1) |
3,747 (99.6) |
14 (0.4) |
3,759 (99.9) |
2 (0.1) |
||||
Moderate | 25,867 (87.9) |
3,545 (12.1) |
28,268 (96.3) |
1,071 (3.7) |
29,123 (99.4) |
180 (0.6) |
29,236 (99.8) |
59 (0.2) |
||||
Poorly | 5,383 (83.3) |
1,076 (16.7) |
6,154 (95.7) |
274 (4.3) |
6,357 (98.8) |
74 (1.2) |
6,395 (99.6) |
28 (0.4) |
||||
Undifferentiated | 828 (84.4) |
153 (15.6) |
946 (96.5) |
34 (3.5) |
966 (98.6) |
14 (1.4) |
978 (99.9) |
1 (0.1) |
||||
Unknown | 3,368 (76.1) |
1,055 (23.9) |
3,987 (91.0) |
394 (9.0) |
4,288 (97.8) |
98 (2.2) |
4,370 (99.6) |
16 (0.4) |
||||
Insurance | <0.001 | <0.001 | 0.044 | 0.237 | ||||||||
Insured | 36,682 (86.8) |
5,595 (13.2) |
40,430 (96.0) |
1,701 (4.0) |
41,752 (99.2) |
352 (0.8) |
41,991 (99.8) |
98 (0.2) |
||||
Uninsured | 1,393 (79.9) |
350 (20.1) |
1,617 (93.1) |
120 (6.9) |
1,718 (98.7) |
23 (1.3) |
1,732 (99.6) |
7 (0.4) |
||||
Unknown | 889 (86.8) |
135 (13.2) |
987 (97.0) |
31 (3.0) |
1,011 (99.5) |
5 (0.5) |
1,015 (99.9) |
1 (0.1) |
||||
Marital status | <0.001 | <0.001 | 0.465 | 0.084 | ||||||||
Married | 20,781 (87.0) |
3,116 (13.0) |
22,945 (96.3) |
876 (3.7) |
23,619 (99.2) |
192 (0.8) |
23,736 (99.8) |
58 (0.2) |
||||
Unmarried | 15,769 (85.6) |
2,650 (14.4) |
17,477 (95.2) |
878 (4.8) |
18,169 (99.1) |
167 (0.9) |
18,290 (99.7) |
47 (0.3) |
||||
Unknown | 2,414 (88.5) |
314 (11.5) |
2,612 (96.4) |
98 (3.6) |
2,693 (99.2) |
21 (0.8) |
2,712 (99.9) |
1 (0.1) |
SD: Standard deviation.
The comparison between patients with and without liver metastasis.
The comparison between patients with and without lung metastasis.
The comparison between patients with and without bone metastasis.
The comparison between patients with and without brain metastasis.