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. 2015 Oct 19;6(36):38967–38982. doi: 10.18632/oncotarget.5734

Figure 4. Prognostic analysis of 14-3-3ε and AKR1B10 in HCC tumors.

Figure 4

A. Representative expressions of 14-3-3ε and AKR1B10 in primary tissues of HCC were examined by immunohistochemical analysis (upper panel). Significant correlation of 14-3-3ε and AKR1B10 expression in primary HCC tumors was analyzed using the Chi-square test (lower panel). B. A Kaplan-Meier analysis indicates that increased levels of AKR1B10 confer a better overall survival (P = 0.003) and C. disease-free survival (P = 0.029) as well as D. a lower metastatic risk (P = 0.002) when compared with no increase of AKR1B10 in 14-3-3ε positive patients.