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A. Vanadate-sensitive ATPase activity of ABCG2 in membrane vesicles was determined with different concentrations of A-803467, as described in materials and methods. A-803467 showed a concentration dependent increase in ATPase activity. B. Effect of MX on the ATPase activity of ABCG2. C. Effect of topotecan on the ATPase activity of ABCG2. All values are the mean ± SD of 3 assays.
