Table 3.
Association of cTnI and in-hospital mortality by Cox regression
| Survived (n) | Expired (n) | HR (95% CI)* | HR (95% CI)† | |
|---|---|---|---|---|
| All patients (n = 580) | ||||
| Troponin I (ng/mL) | ||||
| < 0.06 | 234 | 167 | 1.0 | 1.0 |
| 0.06 - | 28 | 59 | 1.29 (0.95–1.76) | 1.20 (0.89–1.62) |
| 0.21 - | 31 | 61 | 1.39 (1.04–1.88) | 1.39 (1.01–1.89) |
| p-trend | 0.0167 | 0.0307 | ||
| Age ≤ 65 y (n = 366) | ||||
| Troponin I (ng/mL) | ||||
| < 0.06 | 191 | 66 | 1.0 | 1.0 |
| 0.06 - | 19 | 29 | 2.54 (1.63–3.96) | 2.18 (1.40–3.41) |
| 0.21 - | 17 | 44 | 2.28 (1.53–3.40) | 2.05 (1.36–3.09) |
| p-trend | < 0.0001 | < 0.0001 | ||
| Age > 65 y (n = 214) | ||||
| Troponin I (ng/mL) | ||||
| < 0.06 | 43 | 101 | 1.0 | 1.0 |
| 0.06 - | 9 | 30 | 0.76 (0.49–1.18) | 0.74 (0.49–1.12) |
| 0.21 - | 14 | 17 | 0.67 (0.40–1.13) | 0.77 (0.43–1.38) |
| p-trend | 0.0826 | 0.1688 | ||
| p-interaction | < 0.0001 | 0.0090 | ||
*
Analysis of peak cTnI value as a single exposure; adjusted for age, gender, injury type (including MVC, fall, other blunt trauma, penetrating injuries, and other injury types), ISS, admission GCS score, surgical intervention, and preexisting cardiac diseases.
†
Analysis using repeated measures of cTnI levels as time-dependent exposures; adjusted for all potential cofounders mentioned above.