[A]: Mice were sacrificed at days 10, 14, 21, 28, and 35. Tendons were tested for gliding resistance (which represents the work required to flex the digits) by measuring the change in the angle of the MTP joint during incremental loading of the FDL. There is no significant difference in gliding resistance between the vehicle (black line) and Ro 32-3555 treated groups (red line) at any time-point. p>0.05 [B]: Hind paws were also tested for MTP range of motion, which represents the change in MTP flexion angle from the neutral position to 19g of load (heaviest load applied). There are no significant differences in MTP ROM between the vehicle and Ro 32-3555 treated groups at any time-point. p>0.05